Loss to follow-up occurs at all stages in the diagnostic and follow-up period among HIV-infected patients in Guinea-Bissau: a 7-year retrospective cohort study

نویسندگان

  • Bo Langhoff Hønge
  • Sanne Jespersen
  • Pernille Bejer Nordentoft
  • Candida Medina
  • David da Silva
  • Zacarias José da Silva
  • Lars Østergaard
  • Alex Lund Laursen
  • Christian Wejse
  • Amabelia Rodrigues
  • David da Silva
  • Zacarias da Silva
  • Candida Medina
  • Ines Oliviera-Souto
  • Lars Østergaard
  • Alex Laursen
  • Morten Sodemann
  • Peter Aaby
  • Anders Fomsgaard
  • Christian Erikstrup
  • Jesper Eugen-Olsen
  • Christian Wejse
چکیده

OBJECTIVES To describe loss to follow-up (LTFU) at all stages of the HIV programme. DESIGN A retrospective cohort study. SETTING The HIV clinic at Hospital National Simão Mendes in Bissau, Guinea-Bissau. PARTICIPANTS A total of 4080 HIV-infected patients. OUTCOME MEASURES Baseline characteristics, percentages and incidence rates of LTFU as well as LTFU risk factors at four different stages: immediately after HIV diagnosis (stage 1), after the first CD4 cell count and before a follow-up consultation (stage 2), after a follow-up consultation for patients not eligible for antiretroviral treatment (ART; stage 3) and LTFU among patients on ART (stage 4). RESULTS Almost one-third of the patients were lost to the programme before the first consultation where ART initiation is decided; during the 7-year observation period, more than half of the patients had been lost to follow-up (overall incidence rate=51.1 patients lost per 100 person-years). Age below 30 years at inclusion was a risk factor for LTFU at all stages of the HIV programme. The biggest risk factors were body mass index <18.5 kg/m(2) (stage 1), male gender (stage 2), HIV-2 infection (stage 3) and CD4 cell count <200 cells/μL (stage 4). CONCLUSIONS In this study, LTFU constituted a major problem, and this may apply to other similar ART facilities. More than half of the patients were lost to follow-up shortly after enrolment, possibly implying a high mortality. Thus, retention should be given a high priority.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Lack of awareness of treatment failure among HIV-1-infected patients in Guinea-Bissau – a retrospective cohort study

INTRODUCTION With more people receiving antiretroviral treatment (ART), the need to detect treatment failure and switch to second-line ART has also increased. We assessed CD4 cell counts (as a marker of treatment failure), determined the rate of switching to second-line treatment and evaluated mortality related to treatment failure among HIV-infected patients in Guinea-Bissau. METHODS In this...

متن کامل

Early Diagnosis and Intervention for Hearing Loss in Newborns Discharged from Intensive Care Units: a Four-year Follow-up Study in North of Iran

Background Hearing loss is the most common congenital disorder the incidence of which is further increased in the presence of risk factors for hearing loss among newborns admitted to the neonatal intensive care unit (NICU). The aim of this study was early diagnosis and intervention for hearing loss in newborns discharged from NICU. Materials and Methods This prospective cohort study was conduct...

متن کامل

Loss to Follow-up After Newborn Hearing Screening and Its Related Factors

Background: Hearing loss is one of the most common birth defects and early detection of this disorder at birth is not possible without hearing screening. The aim of this study was to determine the frequency of loss to-follow-up after neonatal hearing screening and its related factors in KhoramAbad Province - Iran. Methods: This retrospective correlational study was conducted in the time period...

متن کامل

Outcomes of Arthroscopic Biceps Tenodesis for the Treatment of Failed Type II SLAP Repair: A Minimum 2-Year Follow-Up

Background: To retrospectively review surgical outcomes of prospectively collected data on a series of patients whounderwent revision of a type II SLAP repair to arthroscopic biceps tenodesis due to an unsuccessful outcome.Methods: A retrospective review was performed on a cohort of patients who underwent arthroscopic biceps tenodesisfor a failed type II SLAP repair from 2010 ...

متن کامل

Impact of Covid-19 Pandemic on Some Aspects of HIV Surveillance in North of Iran

 Background and purpose: COVID-19 could potentially disrupt routine care management in health systems. One of such problems is associated with HIV surveillance. The aim of this research was to study the effects of COVID-19 pandemic on HIV care indicators. Materials and methods: This retrospective cohort study was performed using data at individual and aggregate levels obtained from center for ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2013